Why it is important to address the inflammatory environment in allergies
Allergic manifestations such as rhinitis, urticaria, atopic dermatitis, mucosal hyperreactivity, and respiratory symptoms do not depend exclusively on contact with the allergen.
Today we know that the clinical picture results from the interaction between the immune system, inflammatory mediators, the body's oxidative state, and the function of biological barriers.
When the immune system interprets a harmless substance as a threat, IgE antibodies, mast cells, and inflammatory cells are activated, leading to the release of histamine, leukotrienes, prostaglandins, and cytokines.
This biological cascade generates mucosal congestion, itching, edema, skin irritation, and respiratory symptoms.
In this context, supporting the biological environment and the physiological mechanisms of inflammation regulation can represent a complementary approach to lifestyle and any therapeutic strategies indicated by the doctor.
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The rationale for using Lunae
In the context of allergic manifestations and inflammatory hyperactivation, the rationale for using Lunae is based on the presence of natural components with activity aimed at modulating the inflammatory response and oxidative stress.
The formulation is characterized by the combination of bromelain, Boswellia serrata, and tetrahydrocurcuminoids derived from turmeric.
The goal is not to act as a pharmacological antihistamine or replace medical treatments, but to physiologically support the mechanisms that regulate the body's inflammatory response.
Why 1 tablet at lunch and 1 tablet at dinner
The intake of:
1 tablet at lunch
1 tablet at dinner
is based on accompanying the main metabolic and digestive windows of the day, maintaining continuity of support for the physiological processes of inflammatory modulation.
Distributed intake throughout the day can be useful especially during periods characterized by greater allergen exposure or more persistent symptoms.
Boswellia serrata: modulation of the inflammatory cascade
Boswellia serrata is one of the natural substances most studied in the regulation of inflammatory processes.
Its boswellic acids have been studied for their ability to modulate the activity of 5-lipoxygenase (5-LOX), an enzyme involved in the production of leukotrienes.
Leukotrienes represent key mediators in respiratory allergies and asthma because they promote bronchoconstriction, mucosal secretion, and the recruitment of inflammatory cells.
Some experimental studies also suggest a modulating effect on NF-κB activity, one of the main regulators of chronic inflammation.
Bromelain: physiological support of the immune response
Bromelain is an enzyme complex derived from pineapple.
Numerous studies have examined its role in regulating cell migration and modulating certain inflammatory mediators.
In the respiratory field, effects on secretion drainage and mucosal comfort support have been described.
The interest in bromelain stems mainly from its ability to intervene in the inflammatory environment without blocking normal immune processes.
Tetrahydrocurcuminoids: protection from oxidative stress
Allergic reactions generate a significant production of reactive oxygen species.
Tetrahydrocurcuminoids derived from turmeric have been studied for their high antioxidant activity.
Through the modulation of intracellular pathways involved in oxidative stress and cytokine activation, they can contribute to maintaining cellular balance during inflammatory processes.
Allergy, gut, and diet: an integrated view
The most recent evidence suggests that the intestinal immune system actively participates in regulating the allergic response.
For this reason, support with Lunae can be included within a broader strategy that includes:
varied and plant-rich diet
reduction of the dietary inflammatory load
attention to foods that promote histamine release in sensitive individuals
support of intestinal function
adequate intake of polyunsaturated fatty acids
regular physical activity
sleep quality
The rationale for taking Lunae with 1 tablet at lunch and 1 tablet at dinner stems from the goal of supporting the physiological mechanisms of inflammation and oxidative stress control that accompany the allergic response.
In the presence of allergies, the real goal is not only to reduce the symptom but to work on the biological environment that contributes to the body's reactivity.
NOTE: The information in the product sheets on this site is for informational and educational purposes only and does not represent a medical opinion. The published content is not intended to replace the relationship with the doctor or any medical indications, diagnoses, or prescriptions. The information provided describes the ingredients and characteristics of food supplements, designed as support for the balance and well-being of the body within a healthy lifestyle. Food supplements are not medicines and must not be used to prevent, diagnose, treat, or alleviate diseases or pathological conditions.
Bibliography
Galli SJ, Tsai M. IgE and mast cells in allergic disease. Nature Medicine. 2012.
Akdis CA. Mechanisms of allergen-specific immunotherapy. J Allergy Clin Immunol. 2011.
Ammon HP. Boswellic acids and inflammatory pathways. Planta Medica. 2006.
Siddiqui MZ. Boswellia serrata clinical and pharmacological review. Indian Journal of Pharmaceutical Sciences. 2011.
Brien S et al. Bromelain as an anti-inflammatory agent. Cellular and Molecular Life Sciences. 2004.
Hewlings SJ, Kalman DS. Curcumin: review of human studies. Foods. 2017.
Calder PC. Omega-3 fatty acids and inflammatory processes. Nutrients. 2010.
