Allergies result from a complex interaction between the immune system, inflammation, oxidative stress, the gut microbiota, and environmental factors. In recent years, research has shown that controlling low-grade chronic inflammation and oxidative stress can help maintain the body's natural immune balance.
During an allergic reaction, numerous immune cells are activated, including mast cells, eosinophils, and lymphocytes, which release inflammatory mediators such as histamine, leukotrienes, and pro-inflammatory cytokines. These mediators are responsible for typical allergy symptoms, including nasal congestion, itching, watery eyes, hives, and mucous membrane irritation.
Alongside standard therapies and preventive measures, certain natural substances with antioxidant and anti-inflammatory properties can provide valuable support in helping maintain the body's natural balance.
PRODUCT_ITEM
Recommended dosage
1 tablet at breakfast
1 tablet at lunch
Lunae was developed to provide plant-based substances with strong antioxidant properties that support the body's natural inflammatory regulation processes.
In allergic conditions, oxidative stress is one of the biological mechanisms that amplifies the inflammatory response. During immune cell activation, free radicals are produced, which can sustain inflammation and increase tissue sensitivity to allergic stimuli.
Several studies have shown that reducing oxidative stress can help improve immune balance and limit some of the mechanisms involved in allergic conditions (Nadeem et al., Journal of Allergy, 2013).
Inflammation and allergic response
Allergic reactions do not depend solely on the presence of an allergen.
Modern research has shown that there is an important link between chronic inflammation, changes in the gut microbiota, and immune overactivation.
According to Fasano and colleagues, changes in the intestinal barrier can facilitate the passage of antigens and pro-inflammatory substances, contributing to immune system activation (Fasano, Physiological Reviews, 2011).
In this context, it is particularly important to support the body's natural cellular defense mechanisms and the physiological control of oxidative processes.
The role of antioxidants
Plant compounds with antioxidant properties can counteract the excess free radicals produced during inflammatory processes.
Numerous natural polyphenols have been shown to modulate the activity of transcription factors involved in the inflammatory response, such as NF-κB, helping to maintain the balance of inflammatory cytokines (González et al., Nutrients, 2011).
Lunae was designed to provide nutraceutical support focused on cellular protection and maintaining the body's redox balance.
Allergies and oxidative stress
Oxidative stress has been associated with numerous allergic conditions, including:
allergic rhinitis;
asthma;
atopic dermatitis;
food allergies.
Extensive evidence indicates that the accumulation of reactive oxygen species can promote damage to mucous membranes and amplify the production of inflammatory mediators (Nadeem et al., 2013).
For this reason, supporting antioxidant defenses is an important part of a comprehensive approach to the well-being of individuals with allergies.
Lunae and overall well-being
Taking:
1 tablet at breakfast;
1 tablet at lunch;
provides the body throughout the day with natural substances that help:
protect against oxidative stress;
maintain a natural inflammatory balance;
support cellular well-being;
maintain normal immune function;
protect mucous membranes exposed to environmental agents.
Lunae does not replace therapies prescribed by a doctor or serve as a treatment for allergies, but can be part of a broader strategy that includes:
a diet rich in plant-based foods and polyphenols;
maintaining intestinal health;
regular physical activity;
adequate rest;
reducing exposure to irritating environmental factors.
Conclusions
Allergies are multifactorial conditions in which the gut, microbiota, inflammation, and oxidative stress play closely interconnected roles. Maintaining the body's oxidative balance provides important support for the natural functioning of the immune system.
Taking 1 Lunae tablet at breakfast and 1 at lunch provides nutraceutical support focused on antioxidant protection and maintaining inflammatory balance, contributing to the body's overall well-being during periods of greater exposure to allergens.
Bibliography
Nadeem A, Siddiqui N, Alharbi NO, Alharbi MM. Airway and systemic oxidant-antioxidant dysregulation in asthma: a possible scenario of oxidants spill over from lung into blood. Pulmonary Pharmacology & Therapeutics. 2014.
Fasano A. Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity and cancer. Physiological Reviews. 2011;91(1):151-175.
Pawankar R, Canonica GW, Holgate ST, Lockey RF, Blaiss MS. World Allergy Organization White Book on Allergy. 2020.
González R, Ballester I, López-Posadas R, et al. Effects of flavonoids and polyphenols on inflammation and immune response. Nutrients. 2011.
Maintz L, Novak N. Histamine and histamine intolerance. American Journal of Clinical Nutrition. 2007;85(5):1185-1196.
Wopereis H, Oozeer R, Knipping K, Belzer C, Knol J. The first thousand days – intestinal microbiology of early life. Allergy. 2014;69(7):867-879.
