In recent years, neuroscience and integrative medicine have shown that anxiety, chronic stress, mental fatigue, and alterations in adaptive capacity do not depend exclusively on the brain, but involve a biological network connecting the gut, microbiota, immune system, metabolism, and central nervous system.
This system is known as the microbiota–gut–brain axis.
The gut continuously communicates with the nervous system through neural, immune, endocrine, and metabolic pathways. Alterations in the intestinal barrier, changes in the microbiota, and chronic low-grade inflammatory conditions can influence neurochemical regulation and the stress response.
Among the biological systems most involved are:
hypothalamus–pituitary–adrenal (HPA) axis
serotonergic metabolism
dopaminergic regulation
vagus nerve activity
mitochondrial function
production of inflammatory mediators
In conditions of persistent stress, a combination of the following is frequently observed:
reduced resilience
altered intestinal function
impaired mental presence
increased fatigue
altered perception of energy
Within this context, nutritional and phytotherapeutic support can be aimed at maintaining the body's physiological balance.
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For this reason, the following combination is proposed:
1 Cistaloe capsule at lunch
1 Cistaloe capsule at dinner
1 Ferrosa capsule in the morning
4 Bioalcalino 19 capsules in the morning
The nutritional rationale: why support the gut, metabolism, and nervous system simultaneously
The proposed integrated approach is based on three functional levels.
The first level concerns the intestinal environment and physiological digestive function.
The second level concerns energy metabolism and the availability of micronutrients involved in neurochemical physiology.
The third level concerns support for the nervous system and neurovegetative balance.
Cistaloe: supporting the intestinal component of the gut–brain axis
The gut represents one of the main surfaces regulating internal balance.
Intestinal mucosa physiology contributes to maintaining the intestinal barrier, immune communication, and the production of metabolic signals that also influence the nervous system.
In the rationale of the protocol, Cistaloe is included to support the intestinal environment.
Taking:
1 capsule at lunch
1 capsule at dinner
allows support to be distributed throughout the day in relation to physiological digestive activity.
In the context of the previous discussion on the gut–brain axis, support for the intestinal environment is interpreted as indirect support for neurovegetative well-being.
Ferrosa: the role of iron in cognitive function and energy production
Iron is not exclusively involved in hemoglobin production.
From a biological perspective, it is involved in the function of enzymes involved in:
dopamine production
norepinephrine production
mitochondrial function
cellular oxygenation
cognitive performance
Several studies show that states of reduced iron availability can be associated with:
fatigue
reduced concentration
lower stress tolerance
impaired cognitive function
For this reason, the protocol provides:
1 Ferrosa capsule in the morning
The morning dose follows the rationale of supporting the time of day with the greatest energy and cognitive demands.
Bioalcalino 19: support for the nervous system and mental presence
Stress regulation does not depend solely on reducing nervous activation, but also on the body's ability to maintain a state of mental presence and functional balance.
Bioalcalino 19 is included in the protocol as support for psychological well-being and the nervous system.
The choice to take:
4 capsules in the morning
follows the logic of supporting the physiological activation of the day.
In the integrated model discussed in the previous article, support for the nervous system can contribute to maintaining:
stable attention
mental energy
neurovegetative balance
stress adaptation
Dosage schedule
Morning:
1 Ferrosa capsule
4 Bioalcalino 19 capsules
Lunch:
1 Cistaloe capsule
Dinner:
1 Cistaloe capsule
The protocol should be part of a comprehensive strategy that includes a balanced diet, quality sleep, physical activity, and clinical assessment when indicated.
Psychophysical balance arises from the interaction between the gut, metabolism, cognitive function, and neurochemical regulation.
In this perspective, the combination of Cistaloe, Ferrosa, and Bioalcalino 19 is proposed as integrated support for the gut–brain axis, energy metabolism, and the maintenance of neurovegetative well-being.
PLEASE NOTE: The information provided in the product sheets on this website is for informational and educational purposes only and does not represent medical advice. The published content is not intended to replace a relationship with a doctor or any medical advice, diagnosis, or prescriptions. The information provided describes the ingredients and characteristics of food supplements, designed to support the body's balance and well-being within a healthy lifestyle. Food supplements are not medicines and must not be used to prevent, diagnose, treat, or alleviate diseases or pathological conditions.
Bibliography
Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci. 2012.
Mayer EA et al. Gut microbes and the brain. J Neurosci. 2014.
Kelly JR et al. The gut microbiome and psychiatric disorders. Front Cell Neurosci. 2015.
Young SN. How to increase serotonin in the human brain. J Psychiatry Neurosci. 2007.
Beard JL. Iron biology in brain function. J Nutr. 2001.
Zimmermann MB. Iron status and cognitive function. Nutr Rev. 2008.
Lozoff B, Georgieff MK. Iron deficiency and brain development. Semin Pediatr Neurol. 2006.
Sarris J et al. Herbal medicines in psychiatric disorders. CNS Drugs. 2011.
