In the elderly population, attention is often focused on overweight and metabolic diseases, but there is an equally relevant and frequently underdiagnosed condition: undernutrition.
When nutrient intake becomes insufficient relative to the body's needs, metabolic adaptation mechanisms are activated which, over time, can promote the consumption of body protein reserves and the progressive reduction of lean mass.
Muscle tissue is, in fact, one of the body's main functional amino acid stores and participates in maintaining metabolic balance, immune function, recovery capacity, and physical strength.
In the elderly, conditions such as reduced food intake, chronic diseases, convalescence, immobilization, surgery, or increased metabolic needs can accelerate muscle loss processes and promote the development of sarcopenia.
In addition to reduced strength and autonomy, the loss of lean mass can be associated with changes in body composition, increased frailty, reduced bone functionality, and deterioration of quality of life.
For this reason, the modern approach to elderly well-being considers the maintenance of muscle function and metabolic efficiency as an integral part of the overall nutritional strategy.
Within this context, certain nutrients and bioactive compounds have been studied for their involvement in cellular protection mechanisms and the maintenance of musculoskeletal function.
PRODUCT_ITEM
Dosage
Fisiodyn
Take 1 capsule in the morning and 1 capsule in the evening, preferably away from meals or as advised by a healthcare professional.
The intake should be part of a varied, complete diet accompanied by the maintenance of an active lifestyle.
Nutritional support rationale
Fisiodyn is a formulation that combines nutritional components involved in the maintenance of normal muscle and bone metabolism:
- oleuropein;
- polydatin;
- vitamin D;
- vitamin K.
The rationale for the association arises from the growing interest in the role of oxidative stress, cellular metabolism, and musculoskeletal functionality in the processes of physiological aging.
Oleuropein: support for cellular protection systems
Oleuropein is a polyphenol naturally present in olive leaves.
In experimental studies, it has been associated with:
- support of cellular defenses against oxidative stress;
- modulation of physiological inflammatory processes;
- maintenance of redox balance;
- support of cellular metabolic efficiency.
Oxidative stress represents one of the biological mechanisms most studied in age-associated loss of functionality and deterioration of muscle tissue quality.
Polydatin: support for energy metabolism
Polydatin is a natural molecule belonging to the polyphenol family and is considered the glycosylated precursor of resveratrol.
Experimental evidence has highlighted the involvement of polydatin in processes related to:
- mitochondrial function;
- cellular energy regulation;
- protection against oxidative stress;
- metabolic balance.
The rationale for its use is part of the concept of maintaining the physiological adaptive capacity of tissues.
Vitamin D: muscle, strength, and functionality
Vitamin D contributes:
- to the maintenance of normal muscle function;
- to the maintenance of normal bones;
- to the normal absorption of calcium and phosphorus;
- to the normal functioning of the immune system.
The presence of vitamin D receptors in muscle tissue suggests a direct role in muscle physiology.
Numerous clinical observations have associated reduced vitamin D levels with reduced physical performance and muscle strength.
Vitamin K: maintenance of musculoskeletal balance
Vitamin K contributes to the maintenance of normal bones.
In recent years, the concept of the musculoskeletal unit has emerged: the maintenance of skeletal health and muscle function is closely interconnected.
In conditions of reduced lean mass, supporting physiological bone metabolism can represent a complementary element of well-being.
Integrating nutritional support into a comprehensive strategy
Nutritional support finds its purpose within a broader vision of health.
The foundations of lean mass maintenance remain:
- adequate intake of high-quality biological protein;
- correct energy intake;
- regular physical activity;
- maintenance of mobility;
- adequate exposure to light and attention to nutritional status.
In this context, Fisiodyn can be used as nutritional support aimed at maintaining the physiological balance of muscles and bones.
PLEASE NOTE
The information provided in the product sheets on this website is for informational and educational purposes only and does not constitute medical advice.
The published content is not intended to replace the doctor-patient relationship or any medical advice, diagnosis, or prescriptions.
The information provided describes the ingredients and characteristics of food supplements, designed to support the body's balance and well-being within a healthy lifestyle.
Food supplements are not medicines and must not be used to prevent, diagnose, treat, or alleviate diseases or pathological conditions.
Bibliographic references
Cruz-Jentoft AJ et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019.
Cruz-Jentoft AJ, Sayer AA. Sarcopenia. Lancet. 2019.
Volkert D et al. ESPEN guideline on clinical nutrition and hydration in geriatrics. Clinical Nutrition. 2019.
Deutz NEP et al. Protein intake and exercise for optimal muscle function with aging. Clinical Nutrition. 2014.
Bauer J et al. Evidence-based recommendations for dietary protein intake in older people. JAMDA. 2013.
Ceglia L. Vitamin D and skeletal muscle tissue. Molecular Aspects of Medicine. 2008.
Bischoff-Ferrari HA et al. Effect of vitamin D on muscle function and falls. BMJ. 2004.
Rigacci S, Stefani M. Nutraceutical properties of olive polyphenols. Nutrients.
Pangeni R et al. Polydatin: pharmacological activities and molecular mechanisms.
Cederholm T et al. GLIM criteria for the diagnosis of malnutrition. Clinical Nutrition. 2019.
