When stress and inflammation fuel each other
Anxiety, irritability, insomnia, persistent fatigue, difficulty concentrating, and the feeling of not recovering energy are often manifestations of an organism subjected to a state of chronic stress.
The latest scientific knowledge shows that excessive activation of the hypothalamus-pituitary-adrenal axis leads to a persistent production of cortisol, promoting a condition of low-grade chronic inflammation. This phenomenon simultaneously involves the nervous system, gut, metabolism, and immune system.
When inflammation persists over time, a vicious cycle is established:
- increased cortisol;
- neuroinflammation;
- altered mood tone;
- reduced sleep quality;
- increased pain sensitivity;
- worsening ability to adapt to stress.
In these cases, an integrated approach that acts on both inflammatory mechanisms and the neurobiological systems involved in stress regulation can be useful.
PRODUCT_ITEM
MOLTITUDO® Protocol
Morning
Bioalcalino 19
4 capsules in the morning.
Lunch
Lunae
1 tablet during the meal.
Dinner
Lunae
1 tablet during the meal.
Why start the day with Bioalcalino 19
Bioalcalino 19 was developed to support psychological well-being and emotional balance during periods characterized by physical and mental stress. On the MOLTITUDO® website, it is described as support for mental well-being and for maintaining a positive attitude.
The formulation contains a combination of plant extracts that act on different aspects of the stress response:
St. John's Wort and Saffron
They promote normal mood tone and support the neurotransmitter systems involved in emotional regulation.
Several clinical studies have shown that St. John's Wort can be useful in supporting mildly to moderately altered mood tone, while saffron has shown favorable effects on anxious and depressive symptoms.
Hawthorn
It promotes relaxation and mental well-being, proving particularly useful in conditions characterized by nervous tension and neurovegetative hyperactivity.
Devil's Claw and Spirea
They contribute to the physiological control of inflammatory processes and the pain symptoms that frequently accompany chronic stress states.
Cranberry, Red Grape and Maritime Pine
They provide proanthocyanidins and polyphenols with high antioxidant activity, useful in countering oxidative stress associated with systemic chronic inflammation.
Morning intake is particularly rational because it accompanies the organism during the phase of the day when the peak of cortisol production is physiologically observed.
Why combine Lunae with lunch and dinner
If Bioalcalino 19 works mainly on the neuroendocrine and psycho-emotional component of stress, Lunae was formulated to intervene on the physiological control of inflammation.
The formulation combines three particularly studied active ingredients.
Boswellia serrata
Boswellia represents one of the most documented natural substances in the modulation of inflammatory processes.
Boswellic acids contribute to regulating the production of leukotrienes and pro-inflammatory mediators involved in chronic pain and systemic inflammation.
Bromelain
Bromelain is a proteolytic enzyme extracted from pineapple, endowed with anti-edema and anti-inflammatory modulating activity.
Numerous studies document its role in promoting the drainage of inflammatory mediators and the functional recovery of tissues.
Tetrahydrocurcuminoids
They are highly bioavailable metabolites of turmeric characterized by a powerful antioxidant activity.
They act on oxidative stress, neuroinflammation, and cellular protection, processes closely linked to the dysregulation of the stress axis.
The synergy between Bioalcalino 19 and Lunae
The combination of the two products allows intervention simultaneously on two fundamental aspects of the pathophysiology of chronic stress:
Bioalcalino 19
- emotional balance;
- mental well-being;
- stress resilience;
- mood tone support;
- neurovegetative support.
Lunae
- physiological control of inflammation;
- reduction of oxidative stress;
- joint and muscle support;
- support in neuroinflammation processes;
- cellular protection.
This strategy is particularly interesting in subjects who present:
- anxiety associated with physical symptoms;
- chronic stress;
- low-grade systemic inflammation;
- persistent pain;
- muscle tension;
- mental fatigue;
- difficulty concentrating;
- stress-related sleep alterations.
An approach that goes beyond the symptom
Modern evidence on the PNEI shows that the gut, immune system, brain, and endocrine system work as an integrated network.
For this reason, nutraceutical support should be accompanied by:
- anti-inflammatory diet;
- regular physical activity;
- adequate sleep;
- diaphragmatic breathing;
- meditation;
- reduction of the chronic stress load.
The goal is not simply to reduce a symptom, but to promote the recovery of the organism's physiological ability to adapt to stimuli and maintain its internal balance.
Bibliography
McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med. 1998;338:171-179.
Slavich GM, Irwin MR. From stress to inflammation and major depressive disorder. Psychol Bull. 2014;140:774-815.
Miller AH, Raison CL. The role of inflammation in depression. Nat Rev Immunol. 2016;16:22-34.
Cryan JF et al. The microbiota-gut-brain axis. Physiol Rev. 2019;99:1877-2013.
Sarris J et al. Saffron for major depressive disorder. J Integr Med. 2016;14:195-204.
Linde K et al. St John's Wort for depression. Cochrane Database Syst Rev. 2008.
Sengupta K et al. Efficacy and safety of Boswellia serrata extract in osteoarthritis. Arthritis Res Ther. 2008;10.
Pavan R et al. Properties and therapeutic application of bromelain. Biotechnol Res Int. 2012.
Hewlings SJ, Kalman DS. Curcumin: A Review of Its Effects on Human Health. Foods. 2017;6(10):92.
