gender-specific medicine has shown that men and women develop different diseases, symptoms, and therapeutic responses. Women have a greater predisposition to autoimmune diseases, a different immune response, hormone-influenced cardiovascular risk, and a higher incidence of urogenital problems.

Diseases such as rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, scleroderma, and psoriasis predominantly affect the female sex and are characterized by a chronic inflammatory state that can impair energy, quality of life, and cardiovascular health.

For this reason, the MOLTITUDO® nutraceutical protocol based on Ferrosa®, Lunae® and Purisia® was designed to support three fundamental aspects of women's health:

• energy metabolism and cognitive functions;
• control of oxidative stress and chronic inflammation;
• urinary tract wellness and the urogenital environment.

PRODUCT_ITEM

Recommended protocol

Morning

Ferrosa®

• 1 capsule in the morning.

Lunch

Lunae®

• 1 tablet during the meal.

Dinner

Lunae®

• 1 tablet during the meal.

Purisia®

• 1 capsule after dinner.

FERROSA®

Why take it in the morning

In women, the iron requirement is physiologically higher than in men due to menstruation, pregnancy, and breastfeeding.

Numerous studies have shown that even a mild iron deficiency can lead to:

• persistent fatigue;
• reduced concentration;
• attention alterations;
• impaired cognitive performance;
• reduced quality of life.

These aspects are particularly important in women with chronic autoimmune diseases, in which inflammation can alter iron metabolism and promote functional anemia.

Biological rationale

Ferrosa® provides:

• liposomal iron;
• liposomal vitamin C;
• B vitamins.

These nutrients contribute to:

• normal red blood cell formation;
• normal oxygen transport;
• reduced fatigue and tiredness;
• normal cognitive function;
• immune support.

In gender medicine, maintaining adequate iron levels is a fundamental element of women's wellness, especially in women of childbearing age, perimenopause, and patients with chronic inflammatory diseases.

Clinical evidence

• Haas JD, Brownlie T. Journal of Nutrition, 2001.
• Murray-Kolb LE. Journal of Nutrition, 2011.
• Camaschella C. Blood, 2019.

LUNAE®

Nutraceutical support for chronic inflammation in women

Autoimmune diseases are one of the clearest examples of gender-specific medicine.

Lupus affects women about 9 times more than men; Sjögren's syndrome more than 6 times; scleroderma about 4 times; rheumatoid arthritis more than 2 times.

Furthermore, women with autoimmune rheumatic diseases have a significantly higher cardiovascular risk compared to the general population.

Why Lunae® twice a day

Lunae® contains natural substances that act on the biological mechanisms of inflammation:

• Boswellia serrata;
• Bromelain;
• Tetrahydrocurcuminoids.

Taking it at lunch and dinner provides constant support throughout the day.

Scientific rationale

Boswellia

Boswellic acids inhibit 5-lipoxygenase and the synthesis of inflammatory leukotrienes.

Clinical studies show improvements in:

• joint pain;
• stiffness;
• joint function.

Curcuminoids

Tetrahydrocurcuminoids exert a powerful antioxidant activity and modulate NF-kB, TNF-α and IL-6, mediators involved in chronic inflammatory processes.

Bromelain

Contributes to the physiological modulation of the inflammatory response and microcirculation.

Clinical evidence

• Sengupta K. Arthritis Research & Therapy, 2008.
• Yu G. Phytomedicine, 2020.
• Hewlings SJ. Foods, 2017.
• Pavan R. Biotechnology Research International, 2012.

Gender medicine and Lunae®

In women with:

• rheumatoid arthritis;
• lupus;
• Sjögren's syndrome;
• psoriasis;
• psoriatic arthritis;
• menopause associated with low-grade chronic inflammation;

Controlling oxidative stress and inflammation is essential for preserving quality of life, joint function, and cardiovascular health.

PURISIA®

Women's Urinary Tract Wellness

Recurrent urinary tract infections are predominantly a women's issue due to anatomical characteristics and hormonal changes throughout life.

Pregnancy, menopause, and microbiota imbalances can increase susceptibility to lower urinary tract infections.

Why Take Purisia® in the Evening

Purisia® contains:

• D-Mannose;
• Cranberry;
• Birch;
• Hibiscus.

Evening administration promotes greater urinary retention of the active substances during the night.

Biological Rationale

D-Mannose

Reduces the adhesion of Escherichia coli to the bladder mucosa.

Cranberry

Proanthocyanidins (PACs) limit bacterial adhesion to the urothelium.

Birch and Hibiscus

Promote the drainage of body fluids and the function of the urinary tract.

Clinical Evidence

• Kranjčec B. World Journal of Urology, 2014.
• Domenici L. European Review for Medical and Pharmacological Sciences, 2016.
• Fu Z. Journal of Nutrition, 2017.

Gender Medicine and Purisia®

Maintaining the integrity of the urinary tract is a fundamental aspect of women's health, particularly important:

• during menopause;
• in women with microbiota imbalances;
• in patients prone to recurrent cystitis;
• in women with autoimmune conditions that may predispose them to greater mucosal vulnerability.

The Synergy of the MOLTITUDO® Protocol

The combination of Ferrosa®, Lunae®, and Purisia® is based on the principles of gender medicine and personalized medicine.

Ferrosa®

Supports energy, cellular oxygenation, and cognitive function.

Lunae®

Helps modulate the inflammatory and oxidative processes involved in chronic women's diseases.

Purisia®

Promotes urinary tract wellness and a healthy uro-genital environment.

Together, they form a nutraceutical protocol that is particularly interesting for women with:

• autoimmune diseases;
• chronic inflammatory syndromes;
• menopause and perimenopause;
• female cardiovascular predisposition;
• recurrent urinary tract infections;

fatigue and chronic tiredness.