Neuroplasticità: allenare il cervello attraverso movimento, apprendimento e consapevolezza
on October 08, 2026

Neuroplasticity: training the brain through movement, learning, and mindfulness

The brain that changes as we live

Where does a thought come from?

The question seems to belong to philosophy, but it leads directly into the heart of neuroscience. Every thought emerges from the interaction of a complex network of neuronal, biochemical, physiological, and emotional processes. The brain does not function in isolation from the rest of the organism: nervous activity, the endocrine system, breathing, movement, cardiovascular status, sensory perception, and experience continuously contribute to the regulation of behavior.

Thinking, learning, remembering, moving, and adapting to circumstances means modifying, at least in part, the activity of neural networks.

This ability is called neuroplasticity.

Neuroplasticity is the set of processes through which the nervous system modifies its own structure and functioning in response to experience. It can involve the strength of synaptic connections, the formation or elimination of connections, the organization of neural networks, and, under certain conditions, more profound structural changes.

It is one of the biological prerequisites of learning.

When we learn a language, acquire a new motor skill, study a musical instrument, or modify a behavioral strategy, the brain does not merely "store" information: it progressively reorganizes its functional networks.

The starting document highlights precisely how knowledge, study, learning, artistic activities, and the development of motor potential can represent opportunities for training brain plasticity.

The uniqueness of neural potential

Every individual develops a deeply personal neural organization over the course of their life.

The brain is shaped by the interaction between biological heritage and experience: environment, relationships, education, movement, sensory stimuli, learning, and living conditions contribute to the construction of the networks that support perception, memory, emotions, and behavior.

There is therefore no brain that is completely "finished" at the end of development.

Even in adulthood, the nervous system retains a significant capacity for adaptation. This does not mean that the brain can transform without limits or that any disorder can be modified simply through willpower. Rather, it means that experience continues to exert a biological influence on neural networks.

It is precisely this characteristic that makes learning a potentially permanent process.

Experience-dependent plasticity allows the brain to strengthen frequently used circuits and progressively modify those involved in new skills. Repetition, especially when associated with an adequate level of attention and motivation, constitutes one of the main stimuli through which these changes can become consolidated.

Movement and the brain: a bidirectional relationship

Movement is not simply a consequence of brain activity.

It is also one of the stimuli that contribute to modifying it.

Regular physical exercise produces systemic effects affecting metabolism, circulation, vascular function, inflammation, and various neurobiological systems. At the brain level, physical activity has been associated with changes in cognitive function and, in some populations, with structural and functional changes in the regions involved in learning and memory.

One of the studied mechanisms concerns the brain-derived neurotrophic factor (BDNF), a neurotrophin involved in neuronal survival, the growth of connections, and synaptic plasticity processes.

Furthermore, physical activity can promote better metabolic and cardiovascular regulation, important factors for maintaining over time a physiological environment favorable to brain function.

This helps explain why movement should not be considered exclusively as a tool to keep muscles and the cardiovascular system efficient: the brain is an integral part of the response to exercise.

Learning, memory, and new connections

Every form of learning requires a modification of neural networks.

When new information is acquired and subsequently consolidated, the efficiency and strength of communications between specific groups of neurons change. Synaptic plasticity constitutes one of the fundamental mechanisms underlying these phenomena.

Two particularly studied processes are long-term potentiation, or LTP, and long-term depression, or LTD.

LTP can increase over time the effectiveness of synaptic transmission between neurons subjected to specific activation patterns. LTD, on the contrary, can reduce the effectiveness of certain connections. The ability to strengthen some synapses and weaken others allows neural networks to adapt to experience.

Plasticity, therefore, does not simply mean "creating new synapses": it also means selecting, strengthening, weakening, and reorganizing connections based on experiences.

Studying, learning a new skill, practicing music, acquiring a motor skill, or tackling a new cognitive task therefore represent forms of stimulation of the nervous system.

Astrocytes: much more than support cells

Contemporary neuroscience research has progressively changed the conception of astrocytes.

These glial cells are now recognized as active components of neural circuits. They participate in the regulation of the extracellular environment, neuronal metabolism, the availability of neurotransmitters, and communication between cellular elements.

The starting document refers to research published in Nature Neuroscience that studied the role of astrocytes in the ventral tegmental area (VTA) in the regulation of synaptic transmission of dopaminergic neurons.

The VTA is a region involved in important brain circuits associated with motivation, reward, learning, aversion, and locomotor activity.

The cited research showed that the activation of VTA astrocytes can produce a form of long-term potentiation of glutamate-mediated synaptic transmission and modulate the activity of dopaminergic neurons. In the studied experimental model, differences related to sex and development in the maturation of this mechanism also emerged.

This result is particularly interesting because it reinforces a view of the brain as an integrated system, in which neurons and glial cells participate together in the regulation of plasticity.

It is therefore not just a matter of "neurons connecting": plasticity is the result of a complex interaction between different cell types and multiple regulatory systems.

Glutamate, dopamine, and plasticity

Glutamate is the main excitatory neurotransmitter of the central nervous system and plays an essential role in learning and memory processes.

Dopamine, on the other hand, participates in the regulation of motivation, reward, associative learning, and movement control.

These systems do not act separately.

Dopaminergic circuits can modulate the plasticity of neuronal connections based on the relevance of an experience. An experience perceived as important or rewarding can therefore have a greater likelihood of influencing future behavior.

It is one of the reasons why motivation, attention, and emotion can profoundly influence learning.

Learning is not just receiving information: it means attributing meaning to experience, selecting what is relevant, and progressively modifying the networks that support behavior.

Mind and body: a biological relationship, not an opposition

Western cultural tradition has often represented the mind and body as separate entities. Contemporary neuroscience shows, however, how difficult it is to maintain a clear separation.

The brain continuously receives information from the body.

Breathing, heart rate, blood pressure, metabolic status, muscle tension, and signals from internal organs participate in the regulation of nervous activity.

The concept of interoception describes precisely the ability of the nervous system to perceive and integrate signals coming from inside the organism.

The body, therefore, is not simply the "means" through which the brain performs an action: it is a continuous source of information that contributes to the construction of experience.

This helps explain why some practices that combine movement, breathing, attention, and awareness can have effects on psycho-physical well-being.

Tai Chi, Qi Gong, and mindful movement

Mind-body practices, such as Tai Chi and Qi Gong, combine slow movement, postural control, breathing, and attention.

It is not correct to state that these practices "automatically create new synapses" or that they can cure any pathology through neuroplasticity alone. However, there is a growing body of scientific literature that has studied their relationship with balance, motor function, stress, quality of life, and certain cognitive functions.

Their uniqueness may lie precisely in the combination of multiple stimuli:

movement + attention + breathing + coordination + motor learning.

Learning a motor sequence requires planning, balance control, sensory integration, and continuous updating of the gesture.

Constant practice can therefore represent a form of neuro-motor training, especially when performed progressively and mindfully.

Posture as sensory information

Every movement is accompanied by a large amount of sensory information.

Muscles, joints, tendons, the vestibular system, and the visual system provide the brain with information about the body's position in space.

Proprioception allows the nervous system to continuously build a representation of the position and movement of the limbs and trunk.

Posture, therefore, is not merely a mechanical attitude.

It is also information continuously processed by the nervous system.

Training balance, coordination, and postural control therefore means subjecting the brain to a complex sequence of sensory and motor stimuli.

This principle is particularly important with advancing age, when maintaining balance and motor abilities becomes an essential component of fall prevention and the preservation of autonomy.

Constant practice is part of learning

Neuroplasticity is not a switch that is turned on with a single exercise.

Most functional changes associated with learning require repetition, exposure, and consolidation.

Constant practice allows the nervous system to progressively transform an initially voluntary and demanding action into a more efficient skill.

This principle is evident in motor learning: at the beginning, a gesture requires attention, corrections, and conscious control; with practice, it becomes progressively more fluid.

Repetition, however, does not necessarily have to be monotonous. Movement variability, the exploration of new strategies, and adaptation to different conditions can represent further stimuli for the nervous system.

In other words, the brain benefits from both practice and novelty.

Breathing, attention, and stress regulation

Breathing represents one of the few physiological processes that can be voluntarily regulated while maintaining an automatic component.

This makes it particularly interesting in mindfulness practices.

Slow, controlled breathing can alter certain physiological parameters, including the activity of the autonomic nervous system. Breathing and mindfulness techniques have been studied primarily for their potential effects on stress regulation and psychological well-being.

However, it is important to avoid oversimplifications such as "a certain way of breathing automatically increases serotonin, dopamine, oxytocin, and endorphins". The neurochemical systems involved in regulating emotional states are extremely complex and cannot be reduced to a single technique.

The value of breathing practices lies rather in the interaction between arousal regulation, attention, body awareness, and autonomic control.

Thoughts, emotions, and the brain: a word of caution about oversimplifications

The original text offers an interesting reflection on how persistent emotional experiences can influence our behavior and our relationship with our bodies.

Scientific research confirms that chronic stress, adverse experiences, mood disorders, and psychological conditions can be associated with functional and, in some contexts, structural changes in brain circuits.

However, it is important not to turn this into a simplistic model in which a single negative thought would be able to "block" brain plasticity or directly generate a particular illness.

The relationship between thought, emotion, and illness is bidirectional and multifactorial.

Genetics, environment, sleep, diet, physical activity, stress, social relationships, medical conditions, and socioeconomic factors interact with one another.

The brain is also part of this network.

When an experience becomes a habit

One of the most interesting aspects of plasticity is that the same mechanism that allows us to acquire useful behaviors can also contribute to the consolidation of dysfunctional habits.

Repeating a behavioral pattern can make it increasingly automatic.

This principle is evident in motor habits, but it also applies to certain cognitive and emotional behaviors.

The ability to change a habit depends, at least in part, on the ability to introduce new repeated experiences that are significant enough to compete with the previous pattern.

From this perspective, neuroplasticity does not merely represent the possibility of "enhancing" the brain: it also represents the possibility of learning different ways of responding.

This is a particularly important concept in neurological rehabilitation, physiotherapy, occupational therapy, and learning-based psychological interventions.

Neuroplasticity and aging

Aging does not result in a uniform and inevitable loss of cognitive abilities.

The aging brain retains plastic capacities, although some processes may become less efficient and require greater stimulation or more time to consolidate.

Physical activity, lifelong learning, social relationships, adequate sleep, and control of the main cardiovascular risk factors are important components of a lifestyle conducive to brain health.

The goal should not be to "stop the brain from aging," but to maintain cognitive reserve, autonomy, and adaptability for as long as possible.

Acquiring a new skill in adulthood can also become a form of brain stimulation: learning a language, playing an instrument, engaging in an artistic activity, practicing a new sport, or learning a new motor sequence all place new demands on the nervous system.

The home of health as an environment for plasticity

The concept of health can therefore also be interpreted as the ability to maintain a dynamic dialogue between the organism and its environment.

The brain continuously receives stimuli and selects those it considers relevant. Movement, relationships, learning, creativity, and physical activity constitute part of the environment in which the nervous system changes.

A true "home of health" should therefore be conceived not only as a place to intervene when an illness appears, but also as an environment in which to daily exercise the capacities that support autonomy and well-being.

Extraordinary activities are not necessarily required.

Walking, learning, conversing, reading, listening to music, moving, nurturing a relationship, engaging in a manual activity, or practicing a physical discipline can all become opportunities for stimulation.

The difference lies in the continuity and quality of the experience.

The brain needs movement, but also meaning

Neuroplasticity reminds us of one fundamental thing: the brain is not simply the organ that produces thoughts.

It is a biological system that continuously learns from experience.

What we see, hear, learn, and do changes the way neural networks process information. The body continuously sends signals to the brain, and the brain, through the nervous system, organizes motor, cognitive, endocrine, and autonomic responses.

For this reason, neurological well-being cannot be completely separated from the way we live.

Moving, learning, breathing, sleeping, relating to others, and maintaining curiosity about the world are different ways of engaging in dialogue with the nervous system.

Brain plasticity does not promise an unlimited transformation of the organism, nor does it replace medical treatments when an illness is present. However, it offers a scientifically important perspective: throughout life, the brain retains an adaptive and learning capacity that can be supported through appropriate experiences.

From this perspective, training the brain does not merely mean solving cognitive exercises.

It means living experiences that require the brain to learn something new.

And movement can be one of the most comprehensive forms of this experience, because it simultaneously brings together perception, posture, balance, coordination, attention, emotion, and action.

Ultimately, brain health is not just a matter of neurons.

It is also the ability to continue learning, adapting, and actively participating in one's own life.

Bibliographic references

  1. Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons. Nature Neuroscience. 2022. The research cited in the original document describes the involvement of VTA astrocytes in the long-term modulation of synaptic transmission and dopaminergic activity.
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Edited by Nico Martini