BIOALCALINO D OPUS RURI | Natural vegan vitamin D3 from lichen + plant oils rich in omega 3-6-9 | Plant oils 150 ml

– anyone wishing to physiologically support the immune system throughout the year;
– anyone seeking a daily supply of plant-based vitamin D3;
– anyone wishing to support the maintenance of bones and muscle function;
– anyone following a plant-based diet or one lacking in natural sources of vitamin D;
– anyone wishing to supplement with omega-3, 6, and 9 through a blend of plant oils;
– anyone wishing to support skin, cell membranes, and overall well-being;
– men and women seeking an essential formulation free from unnecessary ingredients.

Take 1 ml daily (equivalent to approximately 1 gram of product).
Can be taken as is or diluted in water or another beverage.
Shake before use.
Ingredients: Vitamin D3 from lichen, linseed oil, borage seed oil, evening primrose oil, fenugreek oil.
Liquid formula in an oil matrix.
Vegan formulation.
No preservatives.
No added chemicals.
No unnecessary additives.
No capsule: product in liquid oil solution in a glass bottle.

Ingredients per daily dose (1 gram):
Vitamin D from Cladonia rangiferina (L.) Weber ex F.H. Wigg., oil solution standardized to vitamin D3 ≥1,000,000 IU/g – 2 mg equivalent to vitamin D3: 50 µg (2000 IU) – 1000% NRV
Flaxseed oil (Linum usitatissimum L.) – 250 mg
Borage seed oil (Borago officinalis L.) – 250 mg
Evening primrose oil (Oenothera biennis L.) – 250 mg
Cumin oil (Cuminum cyminum L.) – 250 mg
Naturally occurring lipid profile:
Omega-3
Alpha-linolenic acid (ALA) – 162 mg
Omega-6
Linoleic acid – 539 mg
Gamma-linolenic acid (GLA) – 95 mg
Omega-9
Oleic acid – 237 mg
Other naturally occurring fatty acids:
Palmitic acid – 120 mg
Stearic acid – 55 mg
NRV = Nutrient Reference Values pursuant to Regulation (EU) 1169/2011.

Immune system support
Vitamin D contributes to the normal function of the immune system.
Bone and muscle well-being
Vitamin D supports normal calcium metabolism and contributes to normal muscle function.
Optimized absorption
The natural presence of the lipid matrix promotes the bioavailability of the fat-soluble vitamin.
Cell membrane integrity
Vegetable oils provide fatty acids useful for maintaining normal cell structure.
Skin well-being
Borage and evening primrose contribute to the nourishment and functionality of the skin.
Digestive balance
Cumin promotes digestive function and regular gastrointestinal motility.
Complete plant-based formula
Vitamin D3 from lichen and vegetable oils in a single daily solution.

Is Natural Vitamin D + Omega 3-6-9 vegan?
Yes. The vitamin D3 used is derived from Cladonia rangiferina, and the entire formulation consists exclusively of plant-based ingredients.
When should I take Vitamin D?
It can be taken at any time of day. Many people prefer to take it with a meal.
Are the omegas derived from fish?
No. The omega 3-6-9 present is derived exclusively from vegetable oils.
Can I take the product all year round?
It can be used continuously according to individual needs and the advice of a healthcare professional.
Does the product contain preservatives?
No. The formulation is made without preservatives, without added chemicals, and without unnecessary additives.
How many doses does the bottle contain?
The 150 ml bottle provides approximately 150 daily doses.
Is it suitable for those following a plant-based diet?
Yes, the formulation is compatible with a vegan diet.

Plant-based vitamin D3 from Cladonia rangiferina

Vitamin D3 is one of the most extensively studied micronutrients in recent years. In addition to its established role in calcium and phosphorus metabolism, numerous pieces of evidence demonstrate its involvement in immune function, normal muscle function, and the maintenance of bone health. The skin is also one of the main target organs of vitamin D, which participates in keratinocyte differentiation processes and the maintenance of barrier function.
Main references
Holick MF. The Vitamin D Deficiency Pandemic: Approaches for Diagnosis, Treatment and Prevention. Reviews in Endocrine and Metabolic Disorders. 2017.
Pilz S, Zittermann A, Trummer C, et al. Vitamin D testing and treatment: a narrative review of current evidence. Endocrine Connections. 2019.
Bouillon R, Marcocci C, Carmeliet G, et al. Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions. Endocrine Reviews. 2019.
Pludowski P, Takacs I, Boyanov M, et al. Clinical Practice in the Prevention, Diagnosis and Treatment of Vitamin D Deficiency: Updated Guidelines. Nutrients. 2023.
EFSA Panel on Nutrition, Novel Foods and Food Allergens. Dietary Reference Values for Vitamin D.
Regulation (EU) No 432/2012 on authorized health claims.

Borage Oil (Borrago officinalis)
Borage oil is one of the main natural sources of gamma-linolenic acid (GLA), an omega-6 fatty acid involved in the integrity of cell membranes. Studies are available in the literature regarding the maintenance of skin trophism, the skin's barrier function, and joint well-being. Ministerial indications also recognize its contribution to the functionality of cell membranes and the skin.
Main references
Fan YY, Chapkin RS. Importance of dietary gamma-linolenic acid in human health and nutrition. Journal of Nutrition.
Morse NL. Benefits of Gamma-Linolenic Acid in Clinical Medicine. Alternative Medicine Review.
Ministry of Health. BELFRIT list and Botanicals authorized in food supplements.

Evening Primrose Oil (Oenothera biennis)
Evening primrose oil provides gamma-linolenic acid and linoleic acid, structural components of cell membranes. It has been studied in particular for the maintenance of skin trophism, skin elasticity, and physiological joint function.
Main references
Bayles B, Usatine R. Evening Primrose Oil. American Family Physician.
European Medicines Agency (EMA). Assessment Reports on Oenothera biennis.
Ministry of Health. Botanicals in food supplements.

Flaxseed Oil (Linum usitatissimum)
Flaxseed oil is one of the richest plant sources of alpha-linolenic acid (ALA), an omega-3 precursor. Numerous systematic reviews have highlighted the role of plant-based omega-3s in maintaining lipid metabolism, cell membrane integrity, and physiological inflammatory balance.
Main references
Pan A et al. α-Linolenic Acid and Risk of Cardiovascular Disease. American Journal of Clinical Nutrition.
Rodriguez-Leyva D, Pierce GN. The Impact of Flaxseed on Cardiovascular Health. Canadian Journal of Cardiology.
EFSA Panel on Dietetic Products, Nutrition and Allergies. Scientific Opinions on Omega-3 Fatty Acids.

Cumin Oil (Cuminum cyminum)
Cumin is traditionally used to promote digestive function and regular gastrointestinal motility. In recent years, several clinical studies have also evaluated its potential role in carbohydrate and lipid metabolism and oxidative stress.
Main references
Rahmani AH, Shabrmi FM, Aly SM. Active ingredients of Cuminum cyminum and its therapeutic effects. Indian Journal of Pharmaceutical Sciences.
Sowbhagya HB. Chemistry, Technology and Nutraceutical Functions of Cumin. Critical Reviews in Food Science and Nutrition.

Omega-3, Omega-6 and Omega-9 Fatty Acids
The balance between the different unsaturated fatty acids is a fundamental element for maintaining cell membrane fluidity, intracellular communication, and the physiological inflammatory response. Numerous meta-analyses have confirmed the role of essential fatty acids in maintaining cardiovascular health and the functionality of biological membranes.
Main references
Calder PC. Omega-3 Fatty Acids and Inflammatory Processes. Nutrients. 2020.
Calder PC. Omega-3 Fatty Acids and Cardiovascular Disease. Nature Reviews Cardiology.
EFSA Panel on Dietetic Products, Nutrition and Allergies. Scientific Opinions on Essential Fatty Acids.

Immune System and Chronic Inflammation
The interaction between vitamin D and essential fatty acids is an area of growing scientific interest. Vitamin D modulates numerous aspects of innate and adaptive immunity, while polyunsaturated fatty acids contribute to the production of lipid mediators involved in the physiological resolution of inflammation. Available evidence suggests a complementary role in maintaining immune homeostasis, although further studies on combination formulations are required.
Main references
Aranow C. Vitamin D and the Immune System. Journal of Investigative Medicine.
Calder PC. Nutrition, Immunity and COVID-19. BMJ Nutrition, Prevention & Health.
Guidelines and Reference Documents
EFSA – Dietary Reference Values for Vitamin D.
Regulation (EU) No 432/2012 on authorized health claims.
Ministry of Health – Guidelines on food supplements and Botanicals.
European Food Safety Authority (EFSA) – Scientific Opinions on Essential Fatty Acids.

Scientific Considerations
Bioalcalino D combines a plant source of vitamin D3 obtained from Cladonia rangiferina with plant oils naturally rich in omega-3, omega-6, and omega-9 essential fatty acids. The formulation is aimed at supporting the normal function of the immune system, bone and muscle metabolism, and cell membrane integrity, integrating nutrients with complementary biological mechanisms. Scientific evidence is particularly consolidated for vitamin D, while for borage, evening primrose, flaxseed, and cumin oils, the literature mainly supports their role in maintaining the physiological functionality of cell membranes, the skin, lipid metabolism, and inflammatory balance.

Food supplement. Keep out of reach of children. Do not exceed the recommended daily dose. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. As with any supplement or food supplement, it is important to consult your doctor or therapist before use during pregnancy or breastfeeding, when taking medication, in case of various illnesses or medical conditions, or in view of any kind of medical procedure. Discontinue use in case of adverse reactions and consult your doctor or therapist.

The information provided in the product pages of this website is for informational and educational purposes only and does not constitute medical advice. The published content is not intended to replace consultation with a doctor or any medical advice, diagnosis, or prescriptions. The information provided describes the ingredients and characteristics of food supplements, which are intended to support the body’s balance and well-being as part of a healthy lifestyle. Food supplements are not medicines and must not be used to prevent, diagnose, treat, or alleviate diseases or medical conditions.